Kruiz Header

Top Pet Travel Medications Every Pet Parent Needs to Know (And What Pros Recommend!)

As pet owners, we always want the best for our furry companions, especially when it comes to their health and well-being. But when it comes to preparing for travel, figuring out the right medications can be overwhelming. Just like humans, each pet reacts differently to medications, and what works for one might not be ideal for another. Navigating through anti-anxiety or motion sickness medications can feel a bit scary, especially if you’re worried about how your dog or cat might handle the trip. That’s why here at Kruiz, we will try to help owners navigate the best options for our furry companions.

It’s crucial to run a trial at least a week before your trip to see how your pet reacts to the medication. Whether it’s an anti-anxiety pill or a motion sickness treatment, giving your pet time to adjust can help you avoid any surprises on the road. Every animal is unique, and just like us, their reactions can vary. Testing the medications beforehand can help ensure the trip is as smooth as possible, so your four-legged family members can feel safe, comfortable, and ready for the adventure!

1. Dramamine (Dimenhydrinate) – OTC 

Uses: Motion sickness in dogs and cats
Rating: Dogs: 4/5, Cats: 3.5/5

How it works:
Dramamine blocks histamine receptors in the brain, reducing nausea and vomiting by calming the part of the brain responsible for balance and motion perception.

For Dogs:

Dramamine is effective for mild to moderate motion sickness and is well-tolerated in dogs. However, it can cause drowsiness in some dogs.

For Cats:

While safe for cats, Dramamine can cause more pronounced sedation in felines. Some cats may also experience agitation or disorientation.

Pros:

  • Readily available.
  • Effective for mild nausea.

Cons:

  • Can cause drowsiness, especially in cats.
  • Not suitable for severe motion sickness.

Recommendation:
Dramamine works well for dogs but use it with caution in cats due to their sensitivity to antihistamines. Always consult your vet for appropriate dosing.

Source:

Dramamine for Dogs

2. Benadryl (Diphenhydramine) – OTC

Uses: Mild anxiety, motion sickness, and allergic reactions
Rating: Dogs: 3.5/5, Cats: 3/5

How it works:
Benadryl blocks histamine, reducing allergic reactions and motion sickness. It also has sedative properties, making it useful for mild anxiety in pets.

For Dogs:

Benadryl is effective for mild anxiety and allergies in dogs. However, it can cause drowsiness, and some dogs may react with mild agitation.

For Cats:

Cats are generally more sensitive to diphenhydramine, so it’s not as commonly used for anxiety in felines. Side effects, including sedation and dry mouth, can be more pronounced.

Pros:

  • Easily available.
  • Helps with mild allergies and motion sickness.

Cons:

  • Causes drowsiness, particularly in cats.
  • Less effective for severe anxiety.

Recommendation:
Benadryl is a safe option for both cats and dogs, but it may not be the most effective choice for managing anxiety, especially in cats. Always consult your veterinarian for dosing recommendations.

Source

Benadryl for Cats

Benadryl for Dogs

3. Cerenia (Maropitant) – Prescription

Uses: Motion sickness and nausea in dogs and cats
Rating: Dogs: 5/5, Cats: 4.5/5

How it works:
Cerenia blocks NK1 receptors in the brain, preventing vomiting triggered by motion or other stimuli.

For Dogs:

Cerenia is highly effective for preventing motion sickness in dogs. It lasts up to 24 hours and has minimal side effects.

For Cats:

Cerenia works well for preventing nausea in cats but may cause discomfort upon injection. It is safe for cats, though it may require a slightly different dosing schedule.

Pros:

  • Highly effective for both species.
  • Long duration of action.

Cons:

  • Prescription required.
  • Can be more expensive than OTC options.

Recommendation:
Cerenia is a top-tier option for motion sickness in both dogs and cats. It is safe and effective, but due to its prescription status, you’ll need veterinary guidance.

Source:The anti-emetic efficacy of maropitant (Cerenia) in the treatment of ongoing emesis caused by a wide range of underlying clinical aetiologies in canine patients in Europe
Safety, pharmacokinetics and use of the novel NK-1 receptor antagonist maropitant (Cerenia) for the prevention of emesis and motion sickness in cats

4. Gabapentin – Prescription

Uses: Anxiety and pain relief in dogs and cats
Rating: Dogs: 4.5/5, Cats: 5/5

How it works:
Gabapentin works by decreasing abnormal brain activity and altering how the brain and nervous system perceive pain. It has calming effects on the nervous system, making it useful for managing anxiety and chronic pain in pets.

For Dogs:

Gabapentin is commonly used in dogs to manage anxiety, particularly for events like travel or thunderstorms. It also has analgesic properties and is sometimes used to manage chronic pain. It takes effect within an hour and causes minimal sedation at proper dosages.

For Cats:

Gabapentin is particularly useful for cats because it is effective for managing anxiety, especially in high-stress situations like vet visits or travel. In cats, it can have a mild sedative effect, helping them stay calm without heavy sedation. It is widely used because it is generally well-tolerated.

Pros:

  • Effective for anxiety and pain relief.
  • Well-tolerated by both species.
  • Minimal side effects at proper doses.

Cons:

  • Prescription required.
  • Sedation can occur, especially if the dose is too high.

Recommendation:
Gabapentin is an excellent option for managing anxiety and mild pain in both dogs and cats. It’s highly effective, especially in cats, and provides a gentle calming effect. Veterinary oversight is necessary to ensure proper dosing and to avoid over-sedation.

Source:
Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses

5. Zylkene (Alpha-Casozepine) – OTC

Uses: Anxiety relief in dogs and cats
Rating: Dogs: 4/5, Cats: 4/5

How it works:
Zylkene is derived from milk protein and works by mimicking the calming effects of maternal milk. It helps reduce stress without sedation.

For Dogs:

Zylkene works well for mild to moderate anxiety in dogs. It is particularly effective for pets that experience stress during travel. It has no sedative effects and is generally well-tolerated.

For Cats:

Zylkene is also effective for cats with mild anxiety and is a popular choice for travel-related stress. Like dogs, it does not cause sedation, making it ideal for cats that experience stress without agitation.

Pros:

  • Natural and well-tolerated.
  • No sedative effects.

Cons:

  • Takes a few days to build up in the system.
  • Not effective for severe anxiety.

Recommendation:
Zylkene is a good natural option for managing mild anxiety in both cats and dogs. It’s safe and easy to administer, but it is not ideal for managing severe anxiety or stress.

Source:

Cats at the Vet: The Effect of Alpha-s1 Casozepin

6. Trazodone – Prescription

Uses: Severe anxiety in dogs and cats
Rating: Dogs: 4.5/5, Cats: 3.5/5

How it works:
Trazodone works by increasing serotonin levels in the brain, reducing anxiety and promoting relaxation.

For Dogs:

Trazodone is highly effective for dogs with moderate to severe anxiety. It’s often used for pets that experience significant stress during travel or vet visits. It works quickly, within an hour, but can cause drowsiness in some dogs.

For Cats:

Trazodone can be used for cats, but it’s not as commonly prescribed because cats are more sensitive to its sedative effects. It may be helpful in certain situations, but it’s typically not the first choice for managing anxiety in cats.

Pros:

  • Effective for severe anxiety.
  • Safe for both species under veterinary supervision.

Cons:

  • Can cause sedation, especially in cats.
  • Prescription required.

Recommendation:
Trazodone is an excellent choice for dogs with severe anxiety, but it should be used cautiously in cats due to their sensitivity to its effects. Veterinary supervision is crucial.

Source:
Effects of Trazodone on Behavioral and Physiological Signs of Stress in Dogs

Use of Oral Trazodone for Sedation in Cats

7. Benzodiazepines (e.g., Alprazolam, Diazepam) – Prescription

Uses: Severe anxiety in dogs and cats
Rating: Dogs: 5/5, Cats: 4/5

How it works:
Benzodiazepines work by enhancing the effect of GABA, a neurotransmitter that calms brain activity, leading to reduced anxiety and relaxation.

For Dogs:

Benzodiazepines like alprazolam and diazepam are highly effective for managing severe anxiety in dogs. They work quickly and are useful for managing travel-related stress or sudden anxiety-inducing events.

For Cats:

Cats also benefit from benzodiazepines, though they can be more sensitive to the sedative effects. They are effective for managing severe anxiety, but dosage must be carefully monitored to avoid over-sedation or paradoxical reactions (increased anxiety).

Pros:

  • Effective for severe anxiety.
  • Fast-acting.

Cons:

  • Prescription required.
  • Sedation and potential dependence, especially in cats.

Recommendation:
Benzodiazepines are a highly effective option for managing severe anxiety in both dogs and cats. However, they should only be used under close veterinary supervision, particularly in cats. This class of medications should be used with utmost caution as tolerance can develop rapidly.

Source:
Benzodiazepines: Pros and Cons

Keeping Your Pet Safe: Medication Tips for Pet Owners

Ensuring the health and safety of your pet is a top priority, and that includes proper medication management. Administering medications correctly can help avoid serious complications. Below are some helpful guidelines for safely managing your pet’s medications:

Monitor for Side Effects: After giving your pet any medication, keep an eye out for potential side effects such as vomiting, diarrhea, loss of appetite, or changes in behavior. If you notice anything unusual, contact your veterinarian immediately.

Follow Your Veterinarian’s Instructions: Always administer medications exactly as prescribed by your veterinarian. Incorrect dosing or stopping medication too soon can lead to health complications or make the condition worse.

Store Medications Safely: Keep your pet’s medications separate from human medications to avoid accidental mix-ups. Many human medications can be harmful or even toxic to pets.

Check for Harmful Ingredients in Over-the-Counter Medications: If you are considering an over-the-counter medication for your pet, always consult your veterinarian first. Medications formulated for humans can sometimes contain ingredients that are safe for humans but dangerous for animals.

Keep Medications Out of Reach: Just like with children, it’s important to store medications in a secure location where your pet cannot access them. Pets can easily ingest harmful medications, leading to accidental poisoning.

Conclusion

Traveling with your pet doesn’t have to be stressful if you take the time to plan and prepare. Knowing how your pet will respond to each medication is vital to help you and your pet feel confident as you embark on your journey together.

As always, consult with your veterinarian before starting any new medication. They’ll guide you on the right dosages and medications specific to your pet’s needs; as dosages can vary differently based on their health, weight, age, and species. With the right preparations and trial runs, you can ensure that your dog or cat stays calm, comfortable, and safe throughout your trip. After all, a well-prepared pet makes for a much more enjoyable adventure for everyone. Safe travels to you and your beloved furry friend!

FAQs: Pet Travel Medication Questions

1. Can I bring pet medication on a plane?

Yes, you can bring pet medication on a plane, but there are a few things to keep in mind. Make sure to carry the medication in its original packaging, complete with the prescription label from your veterinarian. This will help avoid any issues at airport security. Additionally, it’s a good idea to pack the medication in your carry-on to ensure easy access during the flight. Always consult with your veterinarian before traveling to ensure that your pet’s medications are appropriate for the journey.

2. What medication is given to dogs while flying?

For dogs flying, veterinarians may prescribe medications to help manage anxiety, motion sickness, or stress. Common medications include:

  • Cerenia (maropitant): This is highly effective for preventing motion sickness and nausea in dogs. It’s long-lasting (up to 24 hours) and has minimal side effects.
  • Trazodone: Often used for dogs with moderate to severe anxiety, it promotes relaxation during the flight.
  • Gabapentin: This medication is effective for managing anxiety and mild pain, providing a calming effect without heavy sedation.
  • Benzodiazepines (e.g., Alprazolam or Diazepam): These can be used for severe anxiety but require close veterinary supervision.

Always consult your veterinarian before giving any medication to ensure the correct dosage and safety for your dog.

3. What can I use to sedate my dog for travel?

For sedating a dog during travel, veterinarians may prescribe sedatives such as:

Trazodone: This medication helps with anxiety and provides a calming effect for dogs with severe anxiety. It’s important to note that full sedation is not recommended for air travel due to the potential for health risks. Instead, medications that gently calm and relax your dog are preferred. Always consult your veterinarian for guidance on safe dosages.

Acepromazine: A tranquilizer that can calm overly active dogs and manage stress.

Gabapentin: Offers a mild sedative effect, helping to calm dogs without heavy sedation.

Always consult your veterinarian before giving any medication to ensure the correct dosage and safety for your dog.

4. How to calm dogs for travel?

To calm your dog for travel, there are several methods you can try:

Comfort Items: Bringing your dog’s favorite blanket or toy can provide comfort in an unfamiliar environment.

Medications: As mentioned, anti-anxiety medications like Trazodone or Gabapentin can be prescribed by a vet to reduce stress during travel.

Pheromone Sprays: Using calming pheromone sprays or collars can help ease mild anxiety.

Crate Training: Getting your dog comfortable with being in a crate before the trip can reduce anxiety related to confinement.

Motion Sickness Medications: If your dog experiences motion sickness, Cerenia or Dramamine can be prescribed to prevent nausea and vomiting.

1. How to safely sedate a cat for travel?

To safely sedate your cat for travel, always consult your veterinarian first. Medications like Gabapentin or Benzodiazepines (e.g., Alprazolam or Diazepam) may be prescribed to help sedate and calm your cat during travel. Gabapentin is commonly recommended for its mild sedative effect and ability to reduce anxiety in cats without causing heavy sedation. Benzodiazepines are effective for severe anxiety but require careful dosage monitoring due to potential sedation and paradoxical reactions. Before travel, it’s essential to test the medication at home to observe how your cat responds and avoid any adverse reactions.

Safety tips: Ensure proper dosing as prescribed by your vet and monitor your cat for any side effects like excessive drowsiness, disorientation, or agitation. Avoid overmedication and follow your vet’s recommendations carefully. Always consult your veterinarian before giving any medication to ensure the correct dosage and safety for your cat.

2. What can I give my cat for travel sickness?

For cats that experience travel sickness, Cerenia (Maropitant) is a highly effective prescription medication that helps prevent nausea and vomiting caused by motion sickness. It is well-tolerated in cats and can last up to 24 hours. Dramamine (Dimenhydrinate), an over-the-counter option, is also available, but it’s important to use it cautiously as it can cause pronounced sedation in cats. Always consult your veterinarian before administering any medication, and do a trial run before the actual trip to observe your cat’s reaction.

Safety tips: Start with a small dose as recommended by your vet and monitor your cat for drowsiness or agitation, especially if using over-the-counter options like Dramamine. Always consult your veterinarian before giving any medication to ensure the correct dosage and safety for your cat.

3. Should I medicate my cat for a flight?

If your cat experiences anxiety, motion sickness, or noise sensitivity during flights, medication may help make the experience less stressful. Gabapentin is a commonly prescribed option for managing anxiety in cats and provides a calming effect without heavy sedation. For cats that struggle with motion sickness, Cerenia can be prescribed to prevent nausea. It’s crucial to test any medication at home before the flight to ensure your cat reacts well.

Safety tips: Always follow your veterinarian’s instructions regarding dosing, and be cautious of over-sedating your cat during the flight, as this could interfere with necessary airport security checks. It’s recommended to trial the medication in a controlled environment at least a week before the flight.

4. What can I give my cat to keep him calm while flying?

For keeping your cat calm during a flight, Gabapentin or Trazodone (for severe anxiety) are effective options that can be prescribed by your veterinarian. Gabapentin provides a mild calming effect and is well-tolerated by most cats, while Trazodone can be used for more severe anxiety but may cause sedation. Over-the-counter options like Zylkene, a natural anxiety-relief supplement, can also help manage mild stress without sedation. Be sure to consult your veterinarian for the right choice based on your cat’s health and specific needs.

Safety tips: Try the medication before the flight to ensure your cat is comfortable with it. Keep a close eye on your cat during the journey and provide a familiar blanket or toy in their carrier to help ease anxiety.

If you have further questions, feel free to reach out Kruiz’s Head of Medication Safety Bryan at Bryan@kruiz.co. Please also consult your vet as well!

Discover more from Kruiz

Subscribe now to keep reading and get access to the full archive.

Continue reading